I feel like an idiot right now.  I’ve had trouble for months getting VR Chat movement to work for me consistently.  I kept having an issue with erroneous movement, with my character often running backwards continuously and for no apparent reason.  My search terms for support didn’t turn up anything useful until tonight.

And it was really obvious.

Support Article

I leave my HOTAS controls plugged in all the time, and one of the throttle axes never quite zeroes out, as I never took the time and didn’t have the knowledge to zero it out.  However, I unplugged those controls, and VRChat now runs fine, at least as far as movement is concerned.  The game crashed on me a second ago due to someone overloading the Hub with effects from their character.